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    "headline": "Gut Bacterium and Metabolite Extend Healthy Lifespan in Mice",
    "dek": "A gut bacterium and its metabolite improve health markers and extend lifespan in mice.",
    "prose": "A study published in Nature Aging on August 25, 2026, reported that the gut bacterium Bifidobacterium pseudocatenulatum and its metabolite 5-aminovaleric acid betaine can alleviate aging hallmarks and extend healthy lifespan in mice. [^1]\n\nWhen aged mice were given 5-aminovaleric acid betaine directly, their memory, motor coordination, and mood-related behaviors all improved. [^2]\n\nResearchers published findings in the journal Nature Aging stating that the quantity of the gut bacteria Bifidobacterium pseudocatenulatum is linked to the aging process. [^3]\n\nThe abundance of the bacterium Bifidobacterium pseudocatenulatum declined sharply with age in both men and women, regardless of gut pattern. [^4]\n\nUsing the MicroAge microbiome aging clock, researchers found that individuals carrying higher levels of Bifidobacterium pseudocatenulatum exhibited a younger biological age. [^5]\n\nResearchers determined that the effect may be related to the substance 5-AVAB, which is produced by the bacteria and whose levels also decrease with age. [^6]\n\nScientists analyzed data from several groups of adults and discovered that the amount of the gut bacteria Bifidobacterium pseudocatenulatum noticeably decreases with age in both men and women. [^7]\n\nThe study observed that people with higher levels of Bifidobacterium pseudocatenulatum had a microbiome corresponding to a younger biological age and better health indicators. [^8]",
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