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    "headline": "UCLA Study Suggests Estrogen Treatment May Ease Menopause Brain Fog",
    "dek": "A new UCLA study indicates a specific estrogen treatment may reduce cognitive symptoms in menopausal women.",
    "prose": "A study published in Scientific Reports suggests that a hormone treatment combining estriol and progesterone may help ease cognitive symptoms such as memory lapses and trouble concentrating in menopausal women. [^1]\n\nA study published in Scientific Reports in 2026 by UCLA Health evaluated a combined therapy of estriol and progesterone on a small group of 20 menopausal women with an average age of 53. [^2]\n\nAfter the 12-month treatment regimen, participants reported significant reductions in brain fog and problems with concentration, working memory, processing speed, verbal memory, and problem-solving. [^3]\n\nDr. Rhonda Voskuhl, a neurologist and senior author of the study at UCLA Health, stated that there is currently no FDA-approved treatment type or dose that specifically targets cognitive symptoms during menopause. [^4]\n\nThe study was an observational case series that followed 20 menopausal women with an average age of 53 over a 12-month period. [^5]\n\nExperiments on middle-aged mice showed that estriol reduced markers of pathology in the hippocampus and improved performance in working memory and spatial tasks. [^6]\n\nResearchers declared that confirmation in larger, placebo-controlled clinical trials using standardized brain imaging and cognitive tests is necessary before considering changes in clinical practice. [^7]",
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      "statement": "A study published in Scientific Reports suggests that a hormone treatment combining estriol and progesterone may help ease cognitive symptoms such as memory lapses and trouble concentrating in menopausal women.",
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      "statement": "Dr. Rhonda Voskuhl, a neurologist and senior author of the study at UCLA Health, stated that there is currently no FDA-approved treatment type or dose that specifically targets cognitive symptoms during menopause.",
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