{
  "story_id": "42060716176f0e3e2db7cb3f526eb5eb",
  "desk": "drm3",
  "revision": 2,
  "published_at": "2026-09-02T14:00:09.000Z",
  "content_hash": "a3dddf8b625b14dae3d5afce557d9b9e084894a03785c5864108dd2191a10531",
  "hash_basis": "sha256 over `headline\\ndek\\nprose`, plus `\\n` + the canonical citations JSON when any source is placed, plus `\\n#blog` for blogs",
  "basis": {
    "headline": "Urine Test Detects 92% of Bladder Cancers in Real-World Study",
    "dek": "A new urine-based test identified 92.2% of bladder cancers in a study of nearly 1,000 patients across seven NHS departments.",
    "prose": "A study led by the University of Birmingham and Nonacus Ltd. involving 964 patients across seven NHS urology departments found that the GALEAS Bladder test identified 71 of 77 bladder cancers (92.2%). [^1]\n\nThe GALEAS Bladder test detected all 17 muscle-invasive bladder cancers (100%) and 35 of 36 high-grade cancers (97.2%) diagnosed during the study. [^2]\n\nThe Galeas urine test identified 92% of bladder cancer cases in an NHS trial. [^3]\n\nFor the 30% of patients with non-visible hematuria, the GALEAS Bladder test identified all bladder cancers (100%), and a negative result was associated with a 100% probability of not having bladder cancer. [^4]\n\nProfessor Richard Bryan said that incorporating the GALEAS Bladder test could result in 730 fewer urgent cystoscopies for every 1,000 patients compared with urgent cystoscopy for everyone, with no loss of net clinical benefit. [^5]\n\nCancer Research UK notes that early detection when symptoms appear can help find tumors at a stage where treatment opportunities are better. [^6]\n\nCommon symptoms of brain tumors include persistent headaches, seizures, nausea, vomiting, sleepiness, changes in behavior or personality, memory issues, weakness on one side of the body, and vision or speech problems. [^7]\n\nMayo Clinic reports that treatment options for brain tumors may include surgery, radiation therapy, radiosurgery, chemotherapy, or targeted therapy. [^8]\n\nThe National Health Service (NHS) states that brain tumor symptoms vary depending on the specific part of the brain affected. [^9]\n\nA negative result from the Galeas urine test meant there was more than a 99% chance that the patient did not have bladder cancer. [^10]\n\nMore than 300,000 cystoscopies are performed in the UK each year, with significant waiting lists in some areas. [^11]\n\nProf Richard Bryan, co-author of the study from Birmingham University, stated that the test showed very promising early performance in a large real-world patient population. [^12]",
    "cited": "[{\"statement\":\"A study led by the University of Birmingham and Nonacus Ltd. involving 964 patients across seven NHS urology departments found that the GALEAS Bladder test identified 71 of 77 bladder cancers (92.2%).\",\"source\":\"Medical Xpress\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-02T14:00:09.000Z\",\"publisher_count\":1,\"sources\":[\"Medical Xpress\"]},{\"statement\":\"The GALEAS Bladder test detected all 17 muscle-invasive bladder cancers (100%) and 35 of 36 high-grade cancers (97.2%) diagnosed during the study.\",\"source\":\"Medical Xpress\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-02T14:00:09.000Z\",\"publisher_count\":1,\"sources\":[\"Medical Xpress\"]},{\"statement\":\"The Galeas urine test identified 92% of bladder cancer cases in an NHS trial.\",\"source\":\"BBC News\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-02T01:39:17.000Z\",\"publisher_count\":1,\"sources\":[\"BBC News\"]},{\"statement\":\"For the 30% of patients with non-visible hematuria, the GALEAS Bladder test identified all bladder cancers (100%), and a negative result was associated with a 100% probability of not having bladder cancer.\",\"source\":\"Medical Xpress\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-02T14:00:09.000Z\",\"publisher_count\":1,\"sources\":[\"Medical Xpress\"]},{\"statement\":\"Professor Richard Bryan said that incorporating the GALEAS Bladder test could result in 730 fewer urgent cystoscopies for every 1,000 patients compared with urgent cystoscopy for everyone, with no loss of net clinical benefit.\",\"source\":\"Medical Xpress\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-02T14:00:09.000Z\",\"publisher_count\":1,\"sources\":[\"Medical Xpress\"]},{\"statement\":\"Cancer Research UK notes that early detection when symptoms appear can help find tumors at a stage where treatment opportunities are better.\",\"source\":\"Media Indonesia\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-01T15:20:00.000Z\",\"publisher_count\":1,\"sources\":[\"Media Indonesia\"]},{\"statement\":\"Common symptoms of brain tumors include persistent headaches, seizures, nausea, vomiting, sleepiness, changes in behavior or personality, memory issues, weakness on one side of the body, and vision or speech problems.\",\"source\":\"Media Indonesia\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-01T15:20:00.000Z\",\"publisher_count\":1,\"sources\":[\"Media Indonesia\"]},{\"statement\":\"Mayo Clinic reports that treatment options for brain tumors may include surgery, radiation therapy, radiosurgery, chemotherapy, or targeted therapy.\",\"source\":\"Media Indonesia\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-01T15:20:00.000Z\",\"publisher_count\":1,\"sources\":[\"Media Indonesia\"]},{\"statement\":\"The National Health Service (NHS) states that brain tumor symptoms vary depending on the specific part of the brain affected.\",\"source\":\"Media Indonesia\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-01T15:20:00.000Z\",\"publisher_count\":1,\"sources\":[\"Media Indonesia\"]},{\"statement\":\"A negative result from the Galeas urine test meant there was more than a 99% chance that the patient did not have bladder cancer.\",\"source\":\"BBC News\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-02T01:39:17.000Z\",\"publisher_count\":1,\"sources\":[\"BBC News\"]},{\"statement\":\"More than 300,000 cystoscopies are performed in the UK each year, with significant waiting lists in some areas.\",\"source\":\"BBC News\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-02T01:39:17.000Z\",\"publisher_count\":1,\"sources\":[\"BBC News\"]},{\"statement\":\"Prof Richard Bryan, co-author of the study from Birmingham University, stated that the test showed very promising early performance in a large real-world patient population.\",\"source\":\"BBC News\",\"instrument\":\"News\",\"claim_key\":null,\"published_at\":\"2026-09-02T01:39:17.000Z\",\"publisher_count\":1,\"sources\":[\"BBC News\"]}]",
    "kind": "news"
  },
  "receipt_verify": "Ed25519 over the dot-joined string `slice_hash.cursor_from.cursor_to.view.view_version.row_count`; public_key and sig are base64url of the raw 32-byte key / 64-byte signature",
  "receipt": null,
  "receipt_note": "this revision predates receipt-keeping (before v0.37.0); the filed row lives in the record",
  "generation_chain": {
    "wire": {
      "stream": "fountain_news",
      "story_id": "898bed84e0b1685da20b1ed841475f50",
      "thread_id": "0579ebc80ce0a336407f2ab436b0b166",
      "thread_label": "Cancer Research UK",
      "novelty": "UPDATE",
      "content_hash": "2a5308d8417dd1b969f411324d436d83154aeb57f19f674b9eaeb46bb70926f9",
      "last_published_at": "2026-09-02T14:00:09.000Z",
      "read_receipt": {
        "slice_hash": "bff706d0b91b9f4763839423c46df3e448ab83cb9be716aef6645f51c84fd704",
        "cursor_from": "eyJ0cyI6IjIwMjYtMDktMDJUMTM6NTU6MDUuMDAwMDAwWiIsImlkIjoiYWNhYmYyOWI5NzVlYzQwOTE2ZmQ0ODdhYWJiMGRmZGIiLCJ2IjoiMSJ9",
        "cursor_to": "eyJ0cyI6IjIwMjYtMDktMDJUMTQ6MjM6MzIuMDAwMDAwWiIsImlkIjoiZTVlMzFkYjQxN2UyYzA0MGU5Nzc1ZWYwNGE4YWE3MTAiLCJ2IjoiMSJ9",
        "view": "v_fountain_news",
        "view_version": "1",
        "row_count": 100,
        "window_days": 3,
        "bytes_scanned": 10113494,
        "credits": 8,
        "price_per_100_rows": 8,
        "sig": "2iCOEBVF4-TfjfzdZF2Bg0ADm6l9x6q3NnXwy70pyYptwlMv7eTsWrZ8Eg9_XYMR-8EL2p_-7_Sjm2mUC8gDAg",
        "public_key": "bMUigy8O0jOnBxQ4Sc-5lwhIZ8LQVAhxMbR7qESVuUE",
        "signer_path": "lakehouse/data-extract/v1",
        "alg": "Ed25519",
        "signed": true
      }
    },
    "written_at": "2026-09-03T00:35:56.640Z"
  },
  "cited_facts": [
    {
      "statement": "A study led by the University of Birmingham and Nonacus Ltd. involving 964 patients across seven NHS urology departments found that the GALEAS Bladder test identified 71 of 77 bladder cancers (92.2%).",
      "source": "Medical Xpress",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-02T14:00:09.000Z",
      "publisher_count": 1,
      "sources": [
        "Medical Xpress"
      ]
    },
    {
      "statement": "The GALEAS Bladder test detected all 17 muscle-invasive bladder cancers (100%) and 35 of 36 high-grade cancers (97.2%) diagnosed during the study.",
      "source": "Medical Xpress",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-02T14:00:09.000Z",
      "publisher_count": 1,
      "sources": [
        "Medical Xpress"
      ]
    },
    {
      "statement": "The Galeas urine test identified 92% of bladder cancer cases in an NHS trial.",
      "source": "BBC News",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-02T01:39:17.000Z",
      "publisher_count": 1,
      "sources": [
        "BBC News"
      ]
    },
    {
      "statement": "For the 30% of patients with non-visible hematuria, the GALEAS Bladder test identified all bladder cancers (100%), and a negative result was associated with a 100% probability of not having bladder cancer.",
      "source": "Medical Xpress",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-02T14:00:09.000Z",
      "publisher_count": 1,
      "sources": [
        "Medical Xpress"
      ]
    },
    {
      "statement": "Professor Richard Bryan said that incorporating the GALEAS Bladder test could result in 730 fewer urgent cystoscopies for every 1,000 patients compared with urgent cystoscopy for everyone, with no loss of net clinical benefit.",
      "source": "Medical Xpress",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-02T14:00:09.000Z",
      "publisher_count": 1,
      "sources": [
        "Medical Xpress"
      ]
    },
    {
      "statement": "Cancer Research UK notes that early detection when symptoms appear can help find tumors at a stage where treatment opportunities are better.",
      "source": "Media Indonesia",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-01T15:20:00.000Z",
      "publisher_count": 1,
      "sources": [
        "Media Indonesia"
      ]
    },
    {
      "statement": "Common symptoms of brain tumors include persistent headaches, seizures, nausea, vomiting, sleepiness, changes in behavior or personality, memory issues, weakness on one side of the body, and vision or speech problems.",
      "source": "Media Indonesia",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-01T15:20:00.000Z",
      "publisher_count": 1,
      "sources": [
        "Media Indonesia"
      ]
    },
    {
      "statement": "Mayo Clinic reports that treatment options for brain tumors may include surgery, radiation therapy, radiosurgery, chemotherapy, or targeted therapy.",
      "source": "Media Indonesia",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-01T15:20:00.000Z",
      "publisher_count": 1,
      "sources": [
        "Media Indonesia"
      ]
    },
    {
      "statement": "The National Health Service (NHS) states that brain tumor symptoms vary depending on the specific part of the brain affected.",
      "source": "Media Indonesia",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-01T15:20:00.000Z",
      "publisher_count": 1,
      "sources": [
        "Media Indonesia"
      ]
    },
    {
      "statement": "A negative result from the Galeas urine test meant there was more than a 99% chance that the patient did not have bladder cancer.",
      "source": "BBC News",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-02T01:39:17.000Z",
      "publisher_count": 1,
      "sources": [
        "BBC News"
      ]
    },
    {
      "statement": "More than 300,000 cystoscopies are performed in the UK each year, with significant waiting lists in some areas.",
      "source": "BBC News",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-02T01:39:17.000Z",
      "publisher_count": 1,
      "sources": [
        "BBC News"
      ]
    },
    {
      "statement": "Prof Richard Bryan, co-author of the study from Birmingham University, stated that the test showed very promising early performance in a large real-world patient population.",
      "source": "BBC News",
      "instrument": "News",
      "claim_key": null,
      "published_at": "2026-09-02T01:39:17.000Z",
      "publisher_count": 1,
      "sources": [
        "BBC News"
      ]
    }
  ],
  "note": "A signature proves who filed this and that it has not changed since. It never makes a claim true."
}